• +44 (0)845 838 2063
  • Free shipping: To the UK and EU countries on all orders

Entourage Effect Of Full Spectrum CBD

By Amelia Fenner-Prowle | 2nd March, 2021 in Wellness | 0 Comments

Entourage Effect Of Full Spectrum CBD
Looking to try CBD? Get 10% off your first order with us when you add the coupon code "FIRSTORDER" to your cart.

With many well-known health benefits, CBD has grown in popularity in recent years. But there are many different CBD products, from CBD oils to CBD face creams, CBD body creams and gummies, and that can confuse some users when it comes to buying or selecting one product or another. One of the questions we must know before choosing a product is what is Full-Spectrum CBD?

You may find that when you search for CBD products, you will see that some claim to contain Full-Spectrum CBD and others, however, CBD isolate. Although it sounds similar, they are terms that refer to different things. In general, users tend to prefer Full-Spectrum CBD, and here's why. 

Cannabinoids & Full-Spectrum CBD

As you may have already guessed, the variety of Cannabinoids present in a product is what determines whether that product is full-spectrum or isolated. To create CBD products, the Cannabinoids must first be extracted from the Hemp Plant through methods such as CO2 extraction. Through this extraction process, other substances are also extracted from the plant such as Flavonoids, Terpenes and other Cannabinoids. Depending on the hemp strain and the extraction method used, the Cannabinoid profile and composition will differ.

For example, Hemp, which is a plant in the Cannabis Sativa family, has very little THC compared to Cannabis Indica strains like Pennywise, which has a 1: 1 ratio of CBD and THC. Depending on the final product they are looking for, companies choose some varieties or others to extract the substances that they are going to use to create their products.

Once the substances are extracted, the company refines the extract to contain certain Cannabinoids from the plant. The content of the refined product is what determines whether it is a full-spectrum CBD product or a CBD isolate.

What is Full Spectrum CBD 

The hemp plant is made up of hundreds of different phytochemicals, including Cannabinoids, Terpenes, Flavonoids, and other substances. Full-spectrum CBD refers to products that not only contain CBD but also have the benefit of other Cannabinoids and plant molecules. In other words, Full-Spectrum CBD contains those substances that are present in the plant.

Cannabinoids, essential oils and Terpenes that are extracted from the plant interact to intensify the therapeutic benefits that each Cannabinoid has separately. This is known as the entourage effect.


The Entourage Effect

The entourage effect is directly related to the effectiveness of a variety of extracts. More than 100 substances have been identified in the hemp plant. Although each has its therapeutic benefits, when combined they work synergistically to provide even better benefits than alone. Until a few years ago, CBD isolate (CBD in its pure form) was believed to be more effective than full-spectrum CBD. However, in 2005 this theory was disproved by a study conducted in Jerusalem Israel by the Lautenberg Center for General Tumor Immunology.

The study found that subjects taking Full-Spectrum CBD experienced greater relief than subjects taking CBD isolate. The results also showed that Full-Spectrum CBD offered a greater effect with higher doses, while the effects of isolated CBD did not vary with increasing doses.

Some people are concerned that Full-Spectrum CBD contains trace amounts of THC. This is the substance that causes psychoactive effects that many CBD users do not want to suffer from. Therefore, we must emphasize that, in these cases, the amount of THC contained in these products is minimal (of a maximum of 0.3%). Therefore, the possibility of suffering psychoactive effects is almost non-existent.

Here are some compounds worth mentioning that are part of the entourage effect of CBD.

 THCV (Tetrahydrocannabivarin) CBC (Cannabichromene)

There are only two carbon atoms difference between THCV and THC. The therapeutic effects of this compound are very similar to THC, Without the Psychoactive effects. 

Effects of THCV:

  • Increases satiety and improves metabolism – Making it a useful weight loss tool
  • Blood sugar – Research shows it can also help regulate blood sugar
  • Antispasmodic properties 

In most cases, CBC is an abundant cannabinoid. Although there are exceptions. This compound is non-psychoactive and offers excellent anxiolytic and antidepressant activity, especially in combination with CBD. Unfortunately, there are few studies to quantify the effects of this cannabinoid, although we can expect to see much more information on this cannabinoid in the near future.

Effects of CBC:

CBG (Cannabigerol) CBN (Cannabinol)

CBG is one of the precursors of other cannabinoids like THC. It inhibits many of the effects of THC by producing the opposite effect (it blocks the activation of serotonin to reduce psychoactive side effects). It is also one of the strongest anti-anxiety cannabinoids found in the plant.

Effects of CBG:

  • Anti-anxiety
  • Adaptogenic
  • Mild sedative
  • Inhibition of some of the effects of THC

CBN is a by-product of THC. As THC breaks down, some of it turns into CBN. This cannabinoid is mostly non-psychoactive, but it will produce some mild psychoactive side effects in some individuals.

This compound is more sedating than most other cannabinoids and is therefore ideal for people who use cannabis for conditions such as insomnia, anxiety, or high stress.

Effects of CBN:

  • Sedative
  • Anxiolytic
  • Appetite stimulation


What Problems is Full Spectrum CBD Best For?

CBD can be very effective on its own for some people. However, the combination of plant extracts with CBD can provide more intense and long-lasting relief. This is why more and more companies in the industry are creating Full-Spectrum CBD products.

Here are some of the issues that full-spectrum CBD can most effectively treat. There are more, but at this stage studies on them remain limited.

Pain and Swelling

Chronic pain and inflammation are one of the main reasons users turn to CBD. Studies have found that the synergistic effects of Full-Spectrum CBD are more effective than CBD isolate in treating inflammatory problems. This is why patients with autoimmune diseases and chronic conditions find that Full-Spectrum CBD is most effective in relieving inflammation and pain. Terpenes alone have great health potential and we should not forget about them.

Anxiety Disorders

Research upholds CBD's ability to treat anxiety. More studies are being conducted every day, some in animals, helping researchers understand how CBD works in the brain.

Studies on CBD and anxiety disorders continue. For now, the results are promising. While THC alone can make anxiety problems worse, CBD can counteract the effects of THC to jointly alleviate PTSD, stress, and other symptoms. By extracting CBD, THC, and other substances like Terpenes, Full-Spectrum CBD appears to be effective with different anxiety-related disorders.

Nausea and Vomiting

In medicine, it has always been thought that marijuana can treat nausea. As it can stimulate the appetite, it also can help with certain eating disorders. The Cannabinoids present in Full-Spectrum CBD can help relieve nausea and vomiting. The trace amounts of THC byproducts that are present in full-spectrum CBD can be very beneficial in reducing symptoms.

THC can control nausea and vomiting by stimulating CB1 receptors in the brain, especially receptors found in the regulating centers of vomiting and nausea. But at the same time, it stimulates the CB1 receptors found in the gastrointestinal tract, and that helps reduce intestinal motility. Activation of this receptor can help improve appetite.

On the other hand, CBD helps to control nausea by influencing the serotonin receptors. It also reduces the release of serotonin, so there is less stimulation of the vomiting control centre found in the brain. Activating CB2 receptors can also help prevent nausea.

Final Thoughts

Many factors determine how Cannabinoids affect the body, from the chemical composition of the person to weight or history with other chemical substances. For many, Full-Spectrum CBD may be better than isolate because it offers all the benefits of the plant. 

There is no question that Full-Spectrum CBD has more health benefits. It seems that Full-Spectrum CBD is the perfect natural remedy for good health.

View our range of Full-Spectrum CBD Oils and Softgels here.

Related Products

Our Product Range


The information on this website is not intended to replace traditional medical treatment, but is offered as additional, complementary information. There are many scientific studies and anecdotal reporting of the far reaching benefits of CBD Oil, and associated CBD products that we feel it is important to bring this information to our customers attention as part of our mission to educate, inform, and promote honest transparency. However, it is important to note that CBD Oil is not a registered medication, it is registered as a natural food supplement.

Alternative therapies should not be used as a substitute for a varied, nutritional and balanced lifestyle, or an alternative to prescribed medication. If you are pregnant, breastfeeding, taking any prescription medication or are currently undergoing medical advice, please consult your doctor before use.

As with most medications, there is no guarantee of specific results from taking CBD, and results can vary from person to person. That said, we are confident in our CBD Oil and associated CBD products and would love to hear from you of your experiences with CBD.

No comments
This thread has been closed from taking new comments.
PROMOTION: Buy 2 Products And Get A 3rd Completely Free