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How Long Does CBD Stay in Your System?

By Amelia Fenner-Prowle | 16th April, 2021 in CBD | 0 Comments

How Long Does CBD Stay in Your System?
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Consumers are becoming more aware of Cannabidiol (CBD) every day. CBD is a potent natural remedy extracted from the Hemp and Cannabis plants. It is not a psychoactive compound which means it won't intoxicate you. The compound in cannabis that causes that "highness" is tetrahydrocannabinol (THC).

CBD is famed for many health benefits. It is said to help with mild pain, sleeplessness, anxiety, and other health conditions. However, there is a lot we do not know about CBD yet. So, you might be wondering how long does CBD stay in your system?

What Happens to Your Body When You Take CBD Oil?

The Endocannabinoid System (ECS) is a complex biochemical system in our body that influences many things. It affects the blood cells that make up the immune system, brain cells, and spinal cord, skin, etc. The system works through receptors present on these cells. There are two of them - CB1 and CB2.

CBD has many health benefits because it can bind to these CB receptors. It also influences other biochemical processes in your body. So, whenever you use CBD, its molecules bind to those receptors and works to:

  • relieve mild pain
  • reduce inflammation
  • manage some forms of seizures
  • manage anxiety, tension and depression
  • improve sleep
  • increase alertness, etc.

How Long Does It Take for CBD to Start Working?

The time it takes CBD to kick in depends on several factors. Notably, the form of CBD you use determines how fast it is going to kick in. CBD is available in various forms. Examples include CBD oil, cream, edibles, tablets, softgels and even CBD vapes.

Typically, it would take longer for edibles and tablets to start working because they must get into your stomach and be digested before the CBD can be absorbed. This could take up to 2 hours.

On the other hand, if you take CBD Oil orally under the tongue, it will get absorbed very quickly into your bloodstream. Your body absorbs it in 15 minutes or thereabouts after it gets into your oral cavity.

What Determines How Long CBD Stays in Your Body?

How long CBD stays in your system depends on a number of factors.

  • Your body system: CBD affects all of us differently. Various cytochrome enzymes break it down in the liver. How well these enzymes act on the compound varies from person to person and affects how fast the body excretes the substance. Also, CBD stays longer in the body of people with higher body mass index (BMI).
  • Dosage: how much CBD you consume strongly affects how long it stays in your system. The more you use it, the longer it is going to remain in your body. This is why it is essential to grade how much you use. Always find out the CBD content of whatever you use from your supplier or the product's container. You need to know both the CBD% and the number of CBDmgs.
  • Frequency: how often you take CBD determines how long it is going to stay in your system. If you take it often, your body can maintain some levels of CBD over time. If you space out the use, your body eliminates the compound before the next time you use it.
  • The CBD form: as we know, there are various forms of CBD on the market. The CBD form you use determines both how soon you feel the impact, and how long it will remain in your system. CBD in vape form will leave your body very quickly while oils, edibles, and topical products will stay longer.

Diet: what you eat affects the absorption and elimination of CBD. Studies show that if you use CBD without eating, the bioavailability is 6%. If you use it with high meals rich in fat, the bioavailability can increase to 25%. Absorption and elimination are slower if you eat a low-fat diet. However, the metabolism and elimination of CBD are faster on an empty stomach.

For How Long Will You Feel the Effects of CBD?

The half-life of Cannabidiol is 18-32 hours. The duration of CBD effects, however, depends on most of the factors we have mentioned before. A very vital factor is how much you consume.

Usually, we do not expect its therapeutic effects to last longer than 6 hours.

What Other Factors Affect How You Respond to CBD?

Apart from the factors we already mentioned, other things affect how individuals respond to CBD use. These include:

  • Sex: some indications suggest your biological sex could determine how your body responds to CBD. In fact, the FDA is conducting research in this area. Women tend to respond better to CBD than men. Some have said this has to do with men having a higher BMI.
  • Other medications: many medications use the same enzymes as CBD for metabolism. If you are using any of these drugs with CBD, it might affect the metabolism of CBD. In which case, it might take longer for your body to remove CBD from your system.

Some health problems: your liver is essential for the removal of CBD from your body. To a much lesser extent, the kidneys are involved too. If you have problems with any of these organs, it might affect its excretion, as such CBD will stay longer in your system.


There is no straightforward answer to how long CBD lasts in your body - many factors determine that. These factors include the form of CBD you take, the dosage, frequency, body system, food, other medications, etc. Because of all the above, we can all respond to CBD a little differently.  

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The information on this website is not intended to replace traditional medical treatment, but is offered as additional, complementary information. There are many scientific studies and anecdotal reporting of the far reaching benefits of CBD Oil, and associated CBD products that we feel it is important to bring this information to our customers attention as part of our mission to educate, inform, and promote honest transparency. However, it is important to note that CBD Oil is not a registered medication, it is registered as a natural food supplement.

Alternative therapies should not be used as a substitute for a varied, nutritional and balanced lifestyle, or an alternative to prescribed medication. If you are pregnant, breastfeeding, taking any prescription medication or are currently undergoing medical advice, please consult your doctor before use.

As with most medications, there is no guarantee of specific results from taking CBD, and results can vary from person to person. That said, we are confident in our CBD Oil and associated CBD products and would love to hear from you of your experiences with CBD.

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